Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771651 | 0.86 | TP53 (0.42) | TP53HTTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1742675 | 0.80 | LMNA (0.53) | TP53HTTCYP1A2SMN1; SMN2LMNA | |
| SCHEMBL9679579 | 0.79 | CKS1B (0.42) | TP53HTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10665580 | 0.78 | TSHR (0.47) | HTTALDH1A1KMT2APDE2AUSP2 | |
| SCHEMBL10662671 | 0.76 | TSHR (0.48) | LMNAALDH1A1KMT2APDE2AUSP2 | |
| SCHEMBL10659671 | 0.76 | TSHR (0.41) | HTTALDH1A1PDE2AUSP2 | |
| SCHEMBL10664738 | 0.76 | TSHR (0.45) | HTTALDH1A1PDE2AUSP2 | |
| SCHEMBL10664401 | 0.76 | TSHR (0.41) | HTTALDH1A1PDE2AUSP2KDM4E | |
| SCHEMBL10490335 | 0.75 | ALDH1A1 (0.45) | TP53HTTCYP1A2SMN1; SMN2LMNA | |
| SCHEMBL10663534 | 0.75 | TSHR (0.45) | HTTALDH1A1PDE2AUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886883-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1989-12-12 | — | — | US | claimed |