Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | EBP | Q15125 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490528 | 1.00 | KMT2A (0.50) | KMT2AMEN1CHRM2NR1I2LMNA | |
| SCHEMBL4535349 | 0.87 | TDP1 (0.51) | KMT2AMEN1LMNAMAPTCYP1A2 | |
| SCHEMBL9879726 | 0.86 | PTPN1 (0.42) | KMT2AMEN1CHRM2NR1I2LMNA | |
| SCHEMBL5125540 | 0.86 | KMT2A (0.48) | KMT2AMEN1CHRM2NR1I2LMNA | |
| SCHEMBL19583495 | 0.86 | KMT2A (0.57) | KMT2AMEN1CHRM2NR1I2LMNA | |
| SCHEMBL9879678 | 0.85 | PTPN1 (0.42) | KMT2AMEN1CHRM2NR1I2LMNA | |
| SCHEMBL11639548 | 0.85 | CHRM2 (0.55) | KMT2AMEN1CHRM2NR1I2LMNA | |
| SCHEMBL11736716 | 0.84 | KMT2A (0.51) | KMT2AMEN1CHRM2NR1I2LMNA | |
| SCHEMBL28760890 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1CHRM2NR1I2LMNA | |
| SCHEMBL23679247 | 0.82 | KMT2A (0.50) | KMT2AMEN1CHRM2NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804747-A | NON-LINEAR OPTICAL ELEMENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-14 | — | — | US | disclosed |
| EP-0293093-A2 | Azo Compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-30 | — | — | EP | disclosed |
| EP-0220042-A2 | Azo compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-29 | — | — | EP | disclosed |