SCHEMBL11736716

SCHEMBL11736716

CCCCCCCCCCCCCCOc1ccccc1NC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
NR1I2 O75469 1/20 0.51
LMNA P02545 1/20 0.51
CHRM2 P08172 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADRA2A P08913 1/20 0.51
MAPT P10636 1/20 0.51
OPRK1 P41145 1/20 0.51
HTR2B P41595 1/20 0.51
SLC6A3 Q01959 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
PTPN1 P18031 3/20 0.49
EBP Q15125 1/20 0.49
SIGMAR1 Q99720 1/20 0.49
APP P05067 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23679247 0.98 KMT2A (0.50) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL11802472 0.93 CYP1A2 (0.56) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL19583495 0.87 KMT2A (0.57) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL13477751 0.87 KMT2A (0.54) KMT2AMEN1LMNAMAPTHTR2B
SCHEMBL10490472 0.84 KMT2A (0.50) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL10490528 0.84 KMT2A (0.50) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL14106780 0.83 KMT2A (0.50) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL9387360 0.82 LMNA (0.62) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL2245919 0.82 LMNA (0.62) KMT2AMEN1NR1I2LMNACHRM2
SCHEMBL2859001 0.82 LMNA (0.62) KMT2AMEN1NR1I2LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4059447-A Photographic material containing oxazolinone-2 couplers AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed