Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 8/20 | 0.35 |
| ▸ | THRA | P10827 | 6/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819537 | 0.83 | HDAC1 (0.43) | HDAC1HDAC4THRBTHRAALDH1A1 | |
| SCHEMBL9458406 | 0.81 | TSHR (0.50) | TSHRHSD17B10 | |
| SCHEMBL5536600 | 0.78 | HDAC1 (0.38) | HDAC1HDAC4THRBTHRAALDH1A1 | |
| SCHEMBL11328438 | 0.77 | TDP1 (0.48) | HDAC1HDAC4THRBTHRAALDH1A1 | |
| SCHEMBL9585097 | 0.77 | TSHR (0.39) | HDAC1HDAC4FFAR1ALDH1A1USP2 | |
| SCHEMBL10341661 | 0.77 | TSHR (0.58) | TSHRHSD17B10 | |
| SCHEMBL6919173 | 0.75 | ALDH1A1 (0.47) | FFAR1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL11336193 | 0.74 | TDP1 (0.52) | HDAC1HDAC4THRBTHRAALDH1A1 | |
| SCHEMBL12989712 | 0.74 | TDP1 (0.52) | HDAC1HDAC4THRBTHRAALDH1A1 | |
| SCHEMBL7791414 | 0.74 | ALDH1A1 (0.40) | HDAC1HDAC4THRBTHRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868241-A | POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE | AMERICAN CYANAMID COMPANY (US) | 1989-09-19 | — | — | US | claimed |
| EP-0231922-A2 | Electron beam and X-ray resists | AMERICAN CYANAMID COMPANY (US) | 1987-08-12 | — | — | EP | claimed |
| US-4868241-A | POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE | AMERICAN CYANAMID COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0231922-A2 | Electron beam and X-ray resists | AMERICAN CYANAMID COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |