Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17906209 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDALOX15ALOX12 | |
| SCHEMBL5429778 | 0.87 | CYP2A6 (0.50) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 | |
| SCHEMBL15458207 | 0.86 | CYP2A6 (0.41) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 | |
| SCHEMBL17906200 | 0.85 | CDK1 (0.42) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 | |
| SCHEMBL7522666 | 0.84 | CYP2A6 (0.48) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 | |
| SCHEMBL15452989 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 | |
| SCHEMBL10621952 | 0.82 | CYP2A6 (0.46) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 | |
| SCHEMBL14330452 | 0.80 | CYP2A6 (0.44) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 | |
| SCHEMBL3976211 | 0.78 | CYP2A6 (0.52) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 | |
| SCHEMBL4024088 | 0.78 | HSD17B10 (0.48) | ALDH1A1HSD17B10HPGDCYP2A6ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3332645-A1 | USE OF SUBSTITUTED PYRIMIDINE DIONES OR THEIR SALTS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS | Bayer Cropscience AG (DE) | 2018-06-13 | — | — | EP | disclosed |
| CN-103717562-A | Cyclic compound, method for producing same, composition, and method for forming resist pattern | MITSUBISHI GAS CHEMICAL CO | 2014-04-09 | — | — | CN | disclosed |
| US-20100179137-A1 | PYRIDONE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-07-15 | — | — | US | disclosed |
| US-4868241-A | POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE | AMERICAN CYANAMID COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0231922-A2 | Electron beam and X-ray resists | AMERICAN CYANAMID COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179137-A1 | PYRIDONE COMPOUND | PTGER4, P2RY4, PTGER1 | ALDH1A1 1440/4885HSD17B10 1378/4885HPGD 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.