Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222928 | 0.89 | ALDH1A1 (0.62) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL10331742 | 0.87 | ABAT (0.76) | CYP2A6ALDH5A1ABATALDH1A1MAPT | |
| SCHEMBL20546774 | 0.87 | CYP2A6 (0.76) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL9607165 | 0.87 | KMT2A (0.61) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL24197431 | 0.87 | CYP2A6 (0.42) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL24197429 | 0.87 | HDAC8 (0.56) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL371285 | 0.87 | ALDH1A1 (0.67) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL10068137 | 0.85 | ALDH1A1 (0.59) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL8807737 | 0.85 | POLB (0.52) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL5429778 | 0.85 | CYP2A6 (0.50) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970579-A | Low melting liquid-crystal mixtures | OWENS-ILLINOIS, INC. (US) | 1976-07-20 | — | — | US | claimed |
| WO-2021142474-A1 | COVALENT ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-15 | — | — | WO | disclosed |
| CN-110229257-B | Polymerizable monomer, curable composition, and resin member | 德山齿科株式会社 | 2021-07-06 | — | — | CN | disclosed |
| CN-112876944-A | Flame-retardant fireproof coiled material | 邓万菁 | 2021-06-01 | — | — | CN | disclosed |
| EP-3187514-B1 | POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER | TOKUYAMA DENTAL CORP (JP) | 2020-07-29 | — | — | EP | disclosed |
| US-20190300472-A1 | POLYMERIZABLE MONOMER, METHOD OF PRODUCING POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER | TOKUYAMA DENTAL CORPORATION (JP) | 2019-10-03 | — | — | US | disclosed |
| EP-3187514-A1 | POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER | Tokuyama Dental Corporation (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-8367743-B2 | Adhesion promoting photoinitiators for UV cured coatings over metal surfaces | BASF SE (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20090104464-A1 | Adhesion promoting photoinitiators for UV cured coatings over metal surfaces | IGM GROUP B.V. (NL) | 2009-04-23 | — | — | US | disclosed |
| WO-2009050116-A2 | ADHESION PROMOTING PHOTOINITIATORS FOR UV CURED COATINGS OVER METAL SURFACES | BASF SE (DE) | 2009-04-23 | — | — | WO | disclosed |
| EP-0202244-A1 | CURED PRODUCTS FROM THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES. | DOW CHEMICAL CO (US) | 1986-11-26 | — | — | EP | disclosed |
| WO-1986006386-A1 | THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1986-11-06 | — | — | WO | disclosed |
| US-4613663-A | Thermoplastic and thermosettable products prepared by reacting nitrogen-containing heterocyclic compounds with aromatic aldehydes | THE DOW CHEMICAL COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
| WO-1986002932-A1 | THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES AND CURED PRODUCTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1986-05-22 | — | — | WO | disclosed |
| US-4575542-A | Thermosettable polystyrylpyridine prepolymer terminated with ethylenically unsaturated groups and cured products therefrom | THE DOW CHEMICAL COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
| US-4543388-A | Thermosettable polymers or prepolymers prepared from polymethylated pyrazines and aromatic polyaldehydes and cured products therefrom | THE DOW CHEMICAL COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| US-4122070-A | Fibers and anisotropic melts of polyazomethines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4048148-A | Polyazomethine fibers and films | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-3970579-A | Low melting liquid-crystal mixtures | OWENS-ILLINOIS, INC. (US) | 1976-07-20 | — | — | US | disclosed |
| US-3948861-A | Polyamide-imides from bis-imide and dialdoxime | RHONE-POULENC S.A. (FR) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104464-A1 | Adhesion promoting photoinitiators for UV cured coatings over metal surfaces | CDH1, PCNA, VCAM1 | CYP2A6 2971/4885HSD17B10 4057/4885ALDH5A1 3914/4885 |
| US-20190300472-A1 | POLYMERIZABLE MONOMER, METHOD OF PRODUCING POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER | CHRM1, CHRM2, H1-0 | CYP2A6 2167/4885HSD17B10 3312/4885ALDH5A1 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.