Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199669 | 0.92 | CYP1B1 (0.56) | CYP1B1ALDH1A1KDM4ELMNAPOLB | |
| Sulfuric Acid SCHEMBL29217851 | 0.92 | CYP1B1 (0.56) | CYP1B1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL29969387 | 0.86 | CYP1B1 (0.67) | CYP1B1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL92102 | 0.86 | CYP1B1 (0.67) | CYP1B1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL2469135 | 0.84 | CYP1B1 (0.64) | CYP1B1ALDH1A1KDM4ELMNAPOLB | |
| Water SCHEMBL3507216 | 0.84 | CYP1B1 (0.64) | CYP1B1ALDH1A1KDM4ELMNAPOLB | |
| Bromide SCHEMBL17510003 | 0.84 | CYP1B1 (0.64) | CYP1B1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL27494119 | 0.78 | GLS (0.52) | CASP3CA9CA1CA2DRD3 | |
| Ethane SCHEMBL11688465 | 0.78 | CYP1B1 (0.53) | CYP1B1ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL28741362 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108854-B1 | DRUG FOR STIMULATING HEPATIC CELL HOMEOSTASIS AND FOR RESTORING THE FUNCTIONAL CAPACITY OF THE HEPATOCYTES | ARCONTHORN LIMITED (GB) | 1986-04-23 | — | — | EP | claimed |
| EP-0108854-A1 | Drug for stimulating hepatic cell homeostasis and for restoring the functional capacity of the hepatocytes | ARCONTHORN LIMITED (GB) | 1984-05-23 | — | — | EP | claimed |
| US-4812512-A | SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES | ROUSSEL UCLAF (FR) | 1989-03-14 | — | — | US | disclosed |
| EP-0108854-B1 | DRUG FOR STIMULATING HEPATIC CELL HOMEOSTASIS AND FOR RESTORING THE FUNCTIONAL CAPACITY OF THE HEPATOCYTES | ARCONTHORN LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |
| US-4511580-A | AMINOETHYLTHIOSULFONIC ACID | ARCONTHORN LIMITED (GB) | 1985-04-16 | — | — | US | disclosed |
| US-4508733-A | AMINOETHANETHIOSULFONIC ACID | ARCONTHORN LIMITED (GB) | 1985-04-02 | — | — | US | disclosed |
| EP-0108854-A1 | Drug for stimulating hepatic cell homeostasis and for restoring the functional capacity of the hepatocytes | ARCONTHORN LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |