Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.67 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.60 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496235 | 0.90 | TBXAS1 (0.56) | CYP19A1HMOX1TBXAS1KMT2A | |
| SCHEMBL3160306 | 0.83 | CYP19A1 (0.71) | CYP19A1HMOX1TBXAS1 | |
| SCHEMBL12045347 | 0.82 | HMOX1 (0.84) | CYP19A1HMOX1TBXAS1PRKCIKMT2A | |
| Hydrochloric Acid SCHEMBL411704 | 0.81 | CYP19A1 (0.69) | CYP19A1HMOX1TBXAS1 | |
| Hydrochloric Acid SCHEMBL9996059 | 0.81 | HMOX1 (0.81) | CYP19A1HMOX1TBXAS1KMT2A | |
| SCHEMBL5655551 | 0.80 | CYP19A1 (0.71) | CYP19A1HMOX1TBXAS1KMT2A | |
| SCHEMBL2749075 | 0.80 | CYP19A1 (0.71) | CYP19A1HMOX1TBXAS1 | |
| SCHEMBL19390253 | 0.80 | CYP19A1 (0.71) | CYP19A1HMOX1TBXAS1PRKCI | |
| SCHEMBL20570009 | 0.80 | CYP19A1 (0.71) | CYP19A1HMOX1TBXAS1 | |
| SCHEMBL11404089 | 0.80 | HMOX1 (0.91) | CYP19A1HMOX1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831045-A | Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| US-4791126-A | Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredients | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0047109-B1 | RHODANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND ALDOSE REDUCTASE INHIBITOR CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |
| US-4464382-A | Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0047109-A1 | Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-10 | — | — | EP | disclosed |