Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496377 | 0.85 | ATM (0.38) | LMNAAKR1C3NFKB1TSHRAKR1C2 | |
| SCHEMBL10492568 | 0.83 | GFER (0.35) | HTR2A | |
| SCHEMBL10492547 | 0.81 | TDP1 (0.38) | TSHR | |
| SCHEMBL10501343 | 0.81 | MAOB (0.50) | CYP2C9HTR2A | |
| SCHEMBL10492505 | 0.81 | NPC1 (0.42) | LMNA | |
| SCHEMBL10492484 | 0.80 | SKP2 (0.44) | HTR2ATSHR | |
| SCHEMBL10492640 | 0.80 | ALDH1A1 (0.37) | PTGS1PTGS2ALOX5LMNATSHR | |
| SCHEMBL10492551 | 0.80 | MAOB (0.36) | HTR2A | |
| SCHEMBL10492793 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL10492742 | 0.80 | ACHE (0.43) | ALOX5LMNANFKB1TSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868225-A | STERICALLY HINDERED META-PHENYLENEDIAMINE CHAIN EXTENDER FOR POLYURETHANES | THE DOW CHEMICAL COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| US-4866208-A | CURING AGENT FOR EPOXY RESINS; EXTENDERS FOR POLYUREA-URETHANE COPOLYMERS | THE DOW CHEMICAL COMPANY (US) | 1989-09-12 | — | — | US | disclosed |
| US-4792623-A | CURING AGENT, EXTENDER | THE DOW CHEMICAL COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0082258-B1 | SUBSTITUTED M-PHENYLENEDIAMINES | THE DOW CHEMICAL COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| EP-0082258-A1 | Substituted m-phenylenediamines | THE DOW CHEMICAL COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |