Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.67 |
| ▸ | HTT | P42858 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10571646 | 1.00 | DNM1 (0.67) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Bromide SCHEMBL10492573 | 0.96 | DNM1 (0.71) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Bromide SCHEMBL10492706 | 0.96 | DNM1 (0.71) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Bromide SCHEMBL10492837 | 0.96 | DNM1 (0.71) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Bromide SCHEMBL10492622 | 0.96 | DNM1 (0.71) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| SCHEMBL13627731 | 0.91 | DNM1 (0.56) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Fluoride Ion SCHEMBL10492723 | 0.88 | HTT (0.62) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL10717643 | 0.84 | DNM1 (0.94) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL28934920 | 0.84 | DNM1 (0.94) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL8150192 | 0.84 | DNM1 (0.94) | DNM1HTTKMT2AHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874785-A | BACTERICIDES | ETHYL CORPORATION (US) | 1989-10-17 | — | — | US | claimed |
| US-4883917-A | Quaternary ammonium compounds | ETHYL CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| US-4874788-A | BACTERICIDES | ETHYL CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| US-4874789-A | BACTERICIDES | ETHYL CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| US-4874785-A | BACTERICIDES | ETHYL CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| US-4874784-A | BACTERICIDES | ETHYL CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| US-4824867-A | BACTERICIDES | ALBERMARLE CORPORATION | 1989-04-25 | — | — | US | disclosed |