Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489112 | 0.81 | BCL2L1 (0.56) | TSHRL3MBTL1BCL2L1BADNOS3 | |
| SCHEMBL6570394 | 0.79 | BCL2L1 (0.54) | TSHRL3MBTL1BCL2L1BADNOS3 | |
| SCHEMBL568779 | 0.78 | TSHR (0.71) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL31430380 | 0.78 | TSHR (0.71) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL135720 | 0.78 | PNMT (0.53) | HPGDMAOAMAOBCES1PNMT | |
| SCHEMBL466394 | 0.77 | BCL2L1 (0.50) | TSHRBCL2L1BADCYP2A6MAOA | |
| SCHEMBL11005936 | 0.77 | TSHR (0.44) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL28373551 | 0.77 | BCL2L1 (0.68) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL4974372 | 0.77 | BCL2L1 (0.60) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL31135519 | 0.76 | TSHR (0.67) | TSHRHPGDL3MBTL1BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837307-A | [1,1'-biphenyl]compounds having a 2,2'-(alkyl)bridge and a 3-yl(substituted)methyl substituent | FMC CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |