SCHEMBL4974372

SCHEMBL4974372

c1cc2c(c(-c3cccc4c3CCCC4)c1)CCCC2

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.60
BAD Q92934 1/20 0.60
TSHR P16473 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.43
HPGD P15428 1/20 0.43
CYP2A6 P11509 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KCNK2 O95069 1/20 0.41
KCNK10 P57789 1/20 0.41
KCNK18 Q7Z418 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 4/20 0.41
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7104246 0.97 BCL2L1 (0.58) BCL2L1BADTSHRL3MBTL1HPGD
SCHEMBL17698887 0.95 BCL2L1 (0.54) BCL2L1BADTSHRL3MBTL1HPGD
SCHEMBL29488244 0.95 BCL2L1 (0.54) BCL2L1BADTSHRL3MBTL1HPGD
Phosphoric Acid SCHEMBL3922743 0.87 BCL2L1 (0.53) BCL2L1BADTSHRL3MBTL1HPGD
SCHEMBL11023731 0.84 PRCP (0.58) BCL2L1BADTSHR
SCHEMBL21814273 0.84 BCL2L1 (0.50) BCL2L1BADTSHRL3MBTL1HPGD
SCHEMBL30285902 0.84 PRCP (0.58) BCL2L1BADTSHR
SCHEMBL4358490 0.83 BCL2L1 (0.48) BCL2L1BADTSHRL3MBTL1HPGD
SCHEMBL9905481 0.81 BCL2L1 (0.43) BCL2L1BADTSHRL3MBTL1MEN1
SCHEMBL3150959 0.81 BCL2L1 (0.43) BCL2L1BADTSHRL3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4508056-A1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX Dow Global Technologies LLC (US) 2025-02-19 EP claimed
WO-2023200935-A1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 WO claimed
US-20130053576-A1 HETEROGENEOUS RHODIUM METAL CATALYSTS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA 2013-02-28 US claimed
US-5750804-A HYDROGENATING 3-ISOCAMPHYLCYCLOHEXANONE USING RUTHENIUM/PHOSPHINE COMPLEX CATALYST IN PRESENCE OF ALKALI METAL OR ALKALINE EARTH METAL AND AMINE BASE TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-05-12 US claimed
EP-0479542-B1 A phosphino binaphthyl compound and transition metal complexes thereof TAKASAGO PERFUMERY CO LTD (JP) 1995-11-29 EP claimed
US-5206399-A 2,2'-BIS(DIPHENYLPHOSPHINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL AND TRANSITION METAL COMPLEX CONTAINING THE SAME AS LIGAND TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-04-27 US claimed
EP-0479542-A1 A phosphino binaphthyl compound and transition metal complexes thereof Takasago International Corporation (JP) 1992-04-08 EP claimed
US-20250257088-A1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-14 US disclosed
US-20230340300-A1 DECORATIVE MATERIAL, DECORATIVE PANEL, ELECTRONIC DEVICE, AND MANUFACTURING METHOD OF DECORATIVE MATERIAL FUJIFILM CORPORATION (JP) 2023-10-26 US disclosed
CN-115403522-A Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN disclosed
US-20220171109-A1 METHOD FOR PRODUCING OPTICALLY ANISOTROPIC LAYER, METHOD FOR PRODUCING LAMINATE, METHOD FOR PRODUCING OPTICALLY ANISOTROPIC LAYER WITH POLARIZER, METHOD FOR PRODUCING LAMINATE WITH POLARIZER, COMPOSITION, AND OPTICALLY ANISOTROPIC LAYER FUJIFILM CORPORATION (JP) 2022-06-02 US disclosed
CN-114375290-A Novel synthetic options for the preparation of (6R,10S) -10- {4- [ 5-chloro-2- (4-chloro-1H-1, 2, 3-triazol-1-yl) phenyl ] -6-oxo-1 (6H) -pyrimidinyl } -1- (dioxomethyl) -6-methyl-1, 4,7,8,9, 10-hexahydro-11, 15- (methylenebridging) pyrazolo [4,3-B ] [1,7] diazacyclotetradecyn-5 (6H) -one 百时美施贵宝公司 2022-04-19 CN disclosed
CN-114195699-A Organic small molecule chiral main body material and application thereof 常州大学 2022-03-18 CN disclosed
US-5563295-A HYDROGENATION OF OLEFINIC CARBOXYLIC ACID USING RUTHENIUM-PHOSPHINE COMPLEX CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-10-08 US disclosed
US-5530150-A HAVING PHOSPHINE AND PHOSPHITE GROUPS IN SAME MOLECULE; CATALYST SELECTIVITY TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-06-25 US disclosed
EP-0479542-B1 A phosphino binaphthyl compound and transition metal complexes thereof TAKASAGO PERFUMERY CO LTD (JP) 1995-11-29 EP disclosed
EP-0673911-A1 Process for producing optically active carboxylic acids and chiral ligands for this purpose Takasago International Corporation (JP) 1995-09-27 EP disclosed
EP-0614902-A1 Phosphine compounds and transition metal-phosphine complexes containing them as ligands Takasago International Corporation (JP) 1994-09-14 EP disclosed
US-5206399-A 2,2'-BIS(DIPHENYLPHOSPHINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL AND TRANSITION METAL COMPLEX CONTAINING THE SAME AS LIGAND TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-04-27 US disclosed
EP-0479542-A1 A phosphino binaphthyl compound and transition metal complexes thereof Takasago International Corporation (JP) 1992-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130053576-A1 HETEROGENEOUS RHODIUM METAL CATALYSTS RRM2, RRM2B, RRS1 BCL2L1 4183/4885BAD 4759/4885TSHR 980/4885
US-20250257088-A1 INDOLE-FUNCTIONALIZED BISPHOSPHORAMIDITES, METHODS FOR THE PREPARATION THEREOF, AND RHODIUM-LIGAND COMPLEX PPIP5K2, INPP5B, PIP4K2B BCL2L1 1676/4885BAD 734/4885TSHR 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.