Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | RECQL | P46063 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820817 | 0.79 | PIM1 (0.41) | MAPTKDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL5820321 | 0.78 | KDM4E (0.50) | MAPTKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL30003545 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL5816866 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL10494235 | 0.75 | XIAP (0.44) | MAPTKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL5818746 | 0.73 | MAPT (0.63) | MAPTKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL29791770 | 0.73 | MAPT (0.63) | MAPTKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL19303804 | 0.71 | MAPT (0.41) | MAPTKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL1560273 | 0.71 | MAPT (0.43) | MAPTKDM4EALDH1A1MAPK1CYP3A4 | |
| SCHEMBL5820540 | 0.69 | PTGS2 (0.39) | MAPTKDM4EALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | disclosed |