Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 4/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494242 | 0.80 | XIAP (0.37) | MAPTEPHX2ALDH1A1GAAHTT | |
| SCHEMBL30002739 | 0.79 | MAPT (0.52) | MAPTALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL9176608 | 0.79 | MAPT (0.52) | MAPTALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL10494191 | 0.79 | EPHX2 (0.56) | MAPTCYP3A4EPHX2ALDH1A1HTT | |
| SCHEMBL19303777 | 0.78 | EGFR (0.38) | MAPTCYP3A4ALDH1A1GAAHTT | |
| SCHEMBL5821723 | 0.78 | EPHX2 (0.57) | MAPTCYP3A4EPHX2GRIN2DGRIN3B | |
| SCHEMBL19303800 | 0.75 | ESR1 (0.37) | MAPTCYP3A4ALDH1A1GAAHTT | |
| SCHEMBL5820817 | 0.75 | PIM1 (0.41) | MAPTEPHX2ALDH1A1GAAKDM4E | |
| SCHEMBL27636156 | 0.74 | TOP1 (0.53) | MAPTCYP3A4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5820540 | 0.73 | PTGS2 (0.39) | MAPTCYP3A4ALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | claimed |
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | disclosed |