Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820817 | 0.82 | PIM1 (0.41) | XIAPEPHX2MAPTKDM4EALDH1A1 | |
| SCHEMBL10494234 | 0.80 | MAPT (0.41) | EPHX2MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL5819298 | 0.78 | HKDC1 (0.50) | MAPTKDM4EUSP2KMT2AMEN1 | |
| SCHEMBL10494191 | 0.75 | EPHX2 (0.56) | EPHX2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL9176608 | 0.74 | MAPT (0.52) | MAPTKDM4EALDH1A1USP2KMT2A | |
| SCHEMBL30002739 | 0.74 | MAPT (0.52) | MAPTKDM4EALDH1A1USP2KMT2A | |
| SCHEMBL5821723 | 0.71 | EPHX2 (0.57) | EPHX2MAPTKDM4EKMT2APOLB | |
| SCHEMBL19303777 | 0.71 | EGFR (0.38) | MAPTKDM4EALDH1A1USP2KMT2A | |
| SCHEMBL5820540 | 0.69 | PTGS2 (0.39) | MAPTKDM4EALDH1A1USP2KMT2A | |
| SCHEMBL5821593 | 0.69 | PTGS2 (0.39) | MAPTKDM4EALDH1A1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | claimed |
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | disclosed |