Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494413 | 1.00 | ADRB2 (0.38) | ADRB2MAOBCAPN1APPPPARG | |
| SCHEMBL10494462 | 1.00 | ADRB2 (0.38) | ADRB2MAOBCAPN1APPPPARG | |
| SCHEMBL10494404 | 1.00 | ADRB2 (0.38) | ADRB2MAOBCAPN1APPPPARG | |
| SCHEMBL10494411 | 1.00 | ADRB2 (0.38) | ADRB2MAOBCAPN1APPPPARG | |
| SCHEMBL14824471 | 0.84 | ADRB2 (0.53) | ADRB2MMP1MMP9KDM4EMEN1 | |
| SCHEMBL2611664 | 0.84 | ADRB2 (0.42) | ADRB2CAPN1MMP1MMP9KDM4E | |
| SCHEMBL11085294 | 0.82 | KDM4E (0.48) | MAOBCAPN1PPARGKDM4EGAA | |
| SCHEMBL2568099 | 0.81 | MMP1 (0.41) | ADRB2MMP1MMP9NPC1RAB9A | |
| SCHEMBL10494330 | 0.80 | ADRB2 (0.48) | ADRB2MAOBCAPN1MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL10494338 | 0.80 | ADRB2 (0.47) | ADRB2MAOBCAPN1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33024-E | Bronchodilating 8-hydroxy-5-(1R)-1-hydroxy-2-(N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)-amino)ethyl) carbostyril and intermediates thereof | TANABE SEIYAKU CO. LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0147719-B1 | NOVEL CARBOSTYRIL DERIVATIVE AND PROCESS FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4579854-A | ADRENERGIC STIMULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1986-04-01 | — | — | US | disclosed |
| EP-0147719-A2 | Novel carbostyril derivative and process for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-10 | — | — | EP | disclosed |