Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12845563 | 0.81 | HDAC1 (0.44) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL5982820 | 0.79 | MAPT (0.59) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL5982816 | 0.79 | MAPT (0.59) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL27881452 | 0.75 | MAPT (0.55) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL1405622 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL27973101 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL1405623 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL10034515 | 0.75 | LMNA (0.56) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL10494616 | 0.74 | MAPT (0.72) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL10494613 | 0.74 | MAPT (0.72) | MAPTRAB9ANPC1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4800195-A | Substituted azo N-phenyl-N'benzoylureas and their use as insecticides and acaricides | THE DOW CHEMICAL COMPANY (US) | 1989-01-24 | — | — | US | disclosed |
| US-4795746-A | Substituted N-phenyl-N'benzoyl ureas and their use as insecticides and acaricides | THE DOW CHEMICAL COMPANY (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0109172-A1 | Novel substituted N-phenyl-N'benzoylureas and their use as insecticides and acaricides | THE DOW CHEMICAL COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |