Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737161 | 0.69 | — | — | |
| SCHEMBL790497 | 0.69 | — | — | |
| SCHEMBL3872048 | 0.67 | — | — | |
| SCHEMBL28321184 | 0.67 | — | — | |
| SCHEMBL2898782 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL29433170 | 0.64 | APEX1 (0.32) | APEX1 | |
| SCHEMBL9116010 | 0.64 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL9065449 | 0.63 | — | — | |
| SCHEMBL8253779 | 0.63 | — | — | |
| SCHEMBL18729625 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871874-A | Process for producing dienes | ETHYL CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |