SCHEMBL10495293

SCHEMBL10495293

CC(=O)OCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.67
GAA P10253 1/20 0.61
GLA P06280 1/20 0.60
BRCA1 P38398 1/20 0.60
ALDH1A1 P00352 3/20 0.58
LMNA P02545 1/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
TSHR P16473 2/20 0.58
POLB P06746 1/20 0.58
APEX1 P27695 1/20 0.58
HSD17B10 Q99714 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
MAPK1 P28482 1/20 0.57
HPGD P15428 3/20 0.56
NPSR1 Q6W5P4 1/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10495302 0.90 ALDH1A1 (0.70) SMN1; SMN2GAAGLABRCA1ALDH1A1
SCHEMBL28801777 0.89 ALDH1A1 (0.64) SMN1; SMN2GAAALDH1A1LMNAKMT2A
SCHEMBL18470154 0.86 ALDH1A1 (0.57) SMN1; SMN2GAAGLABRCA1ALDH1A1
SCHEMBL7340478 0.84 HSD17B10 (0.60) SMN1; SMN2GAAGLABRCA1ALDH1A1
SCHEMBL210721 0.84 SMN1; SMN2 (0.60) SMN1; SMN2GAAGLABRCA1ALDH1A1
SCHEMBL29631612 0.84 SMN1; SMN2 (0.60) SMN1; SMN2GAAGLABRCA1ALDH1A1
SCHEMBL11000826 0.83 ALDH1A1 (0.63) SMN1; SMN2GAAGLABRCA1ALDH1A1
SCHEMBL12930206 0.83 CES1 (0.63) ALDH1A1MEN1KMT2A
SCHEMBL34474429 0.83 SMN1; SMN2 (0.67) SMN1; SMN2GAAGLABRCA1ALDH1A1
SCHEMBL28463507 0.83 SMN1; SMN2 (0.67) SMN1; SMN2GAAGLABRCA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2387735-B1 NONPOLYMERIC BINDERS FOR SEMICONDUCTOR SUBSTRATE COATINGS FUJIFILM ELECTRONIC MAT USA INC (US) 2019-03-13 EP disclosed
US-RE32868-E Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1989-02-14 US disclosed
US-4395417-A Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1983-07-26 US disclosed