Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495644 | 1.00 | APP (0.48) | APPCYP19A1MAOAMAOBKMT2A | |
| SCHEMBL27606199 | 0.81 | ALDH1A1 (0.42) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL9605432 | 0.81 | NFE2L2 (0.45) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL30299480 | 0.81 | KDM4E (0.57) | CYP19A1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL27588373 | 0.81 | NFE2L2 (0.45) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL6333011 | 0.80 | MEN1 (0.64) | MAOBKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6333009 | 0.80 | MEN1 (0.64) | MAOBKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1099648 | 0.79 | MAPT (0.61) | APPCYP19A1MAOAMAOBKMT2A | |
| SCHEMBL1099649 | 0.79 | MAPT (0.61) | APPCYP19A1MAOAMAOBKMT2A | |
| SCHEMBL10495642 | 0.77 | KMT2A (0.41) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886801-A | Diazine-ethenylphenyl oxamic acids and esters and salts thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1989-12-12 | — | — | US | disclosed |
| US-4788198-A | ANTIALLERGENS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0137979-B1 | DIAZINE-ETHENYLPHENYL OXAMIC ACIDS AND ESTERS AND SALTS THEREOF | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1988-10-26 | — | — | EP | disclosed |
| US-4681884-A | ANTIALLERGEN, ANTIINFLAMMATORY | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1987-07-21 | — | — | US | disclosed |
| EP-0137979-A1 | Diazine-ethenylphenyl oxamic acids and esters and salts thereof | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1985-04-24 | — | — | EP | disclosed |