Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495643 | 1.00 | RAB9A (0.57) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL10387039 | 0.87 | KMT2A (0.68) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL10387037 | 0.87 | KMT2A (0.68) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL660647 | 0.84 | NPC1 (0.60) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL660646 | 0.84 | NPC1 (0.60) | RAB9ANPC1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL9388184 | 0.83 | NPC1 (0.58) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL14935499 | 0.81 | MAPT (0.69) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11049170 | 0.81 | MAPT (0.69) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL9978289 | 0.81 | MAPT (0.69) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL11299049 | 0.79 | MAPT (0.67) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886801-A | Diazine-ethenylphenyl oxamic acids and esters and salts thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1989-12-12 | — | — | US | disclosed |
| US-4788198-A | ANTIALLERGENS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0137979-B1 | DIAZINE-ETHENYLPHENYL OXAMIC ACIDS AND ESTERS AND SALTS THEREOF | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1988-10-26 | — | — | EP | disclosed |
| US-4681884-A | ANTIALLERGEN, ANTIINFLAMMATORY | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1987-07-21 | — | — | US | disclosed |
| EP-0137979-A1 | Diazine-ethenylphenyl oxamic acids and esters and salts thereof | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1985-04-24 | — | — | EP | disclosed |