SCHEMBL1049567

SCHEMBL1049567

CCc1cccc([C]=O)c1[C]=O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.45
GABRB2 P47870 4/20 0.45
DAO P14920 1/20 0.33
FFAR1 O14842 1/20 0.32
PDK2 Q15119 1/20 0.32
MGLL Q99685 1/20 0.31
KCNH2 Q12809 2/20 0.31
SCN5A Q14524 2/20 0.31
CYP3A4 P08684 1/20 0.30
HTR1A P08908 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
CACNA1C Q13936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5970609 0.86 GABRA1 (0.52) GABRA1GABRB2DAOPDK2MGLL
SCHEMBL217965 0.83 BID (0.37) GABRA1GABRB2CYP3A4
SCHEMBL1644574 0.81 BID (0.43) KCNH2
SCHEMBL3302964 0.80 BID (0.45) KCNH2
SCHEMBL535892 0.79 GABRA1 (0.45) GABRA1GABRB2FFAR1MGLL
SCHEMBL1535598 0.78 GABRA1 (0.45) GABRA1GABRB2DAOFFAR1CYP3A4
SCHEMBL9849127 0.78 GABRA1 (0.45) GABRA1GABRB2DAOFFAR1PDK2
SCHEMBL1965147 0.78 CYP3A4 (0.33) CYP3A4
SCHEMBL2924588 0.78 FFAR1 (0.38) GABRA1GABRB2FFAR1
SCHEMBL4952691 0.78 GABRA1 (0.44) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7093664-B2 One-time use composite tool formed of fibers and a biodegradable resin HALLIBURTON ENERGY SERVICES, INC. (US) 2006-08-22 US claimed
US-20050205265-A1 One-time use composite tool formed of fibers and a biodegradable resin HALLIBURTON EENRGY SERVICES, INC. 2005-09-22 US claimed
US-4057672-A Compounded polyvinyl chloride THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-11-08 US claimed
WO-2024106426-A1 CELLULOSE RESIN COMPOSITION AND MOLDED BODY USING SAME 日本電気株式会社 2024-05-23 WO disclosed
WO-2024106436-A1 CELLULOSE RESIN COMPOSITION AND MOLDED BODY USING SAME 日本電気株式会社 2024-05-23 WO disclosed
CN-115161879-A Method for preparing polyvinyl butyral micro-nano fiber through rotor centrifugal spinning and application 广东职业技术学院 2022-10-11 CN disclosed
CN-113861315-B Polyvinyl butyral with sound insulation performance and preparation method thereof 忠信(清远)光伏材料科技有限公司 2022-07-01 CN disclosed
CN-113909738-A Preparation method and application of ceramic soldering tin head surface treatment coating 佛山市摩陶新材料科技有限公司 2022-01-11 CN disclosed
CN-109453411-B Chitosan dressing 广州润虹医药科技股份有限公司 2021-11-26 CN disclosed
CN-210904261-U Self-adhesive hemostatic artificial dura mater repair tablet 孟国路 2020-07-03 CN disclosed
CN-108778768-B Lithographic printing plate precursor, laminate thereof, and method for producing lithographic printing plate precursor 富士胶片株式会社 2020-04-03 CN disclosed
EP-0467164-A2 Flupirtine in combination with antiparkinsonica against muscle bracing ASTA Medica Aktiengesellschaft (DE) 1992-01-22 EP disclosed
US-5068233-A For treatment of asthma, antiallergens or antihistamines ASTA PHARMA AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
EP-0277352-B1 SYNERGISTIC MIXTURE OF AZELASTINE AND THEOPHYLLINE OR OF AZELASTINE AND BETA-MIMETICS ASTA Pharma Aktiengesellschaft (DE) 1991-10-16 EP disclosed
EP-0419998-A2 Use of alkylphosphonic acid derivatives for the treatment of psoriasis ASTA Medica Aktiengesellschaft (DE) 1991-04-03 EP disclosed
EP-0378086-A2 Use of the agent azelastine in the treatment of psoriasis ASTA Medica Aktiengesellschaft (DE) 1990-07-18 EP disclosed
US-4938748-A Urinary drainage container comprising external source of biocide ALZA CORPORATION, A CORP. OF DE 1990-07-03 US disclosed
EP-0357318-A2 Urinary drainage container comprising external source of biocide ALZA CORPORATION (US) 1990-03-07 EP disclosed
EP-0324947-A1 Synergistic combination of decarboxylase inhibitors and L-dopa pellets ASTA Medica Aktiengesellschaft (DE) 1989-07-26 EP disclosed
EP-0277352-A1 Synergistic mixture of azelastine and theophylline or of azelastine and beta-mimetics ASTA Pharma Aktiengesellschaft (DE) 1988-08-10 EP disclosed