Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910448 | 0.84 | DAO (0.38) | GABRA1GABRB2FFAR1MAPTCYP2D6 | |
| SCHEMBL27249197 | 0.82 | FFAR1 (0.54) | GABRA1GABRB2FFAR1MGLLMAPT | |
| SCHEMBL1141490 | 0.82 | GABRA1 (0.45) | GABRA1GABRB2FFAR1MGLLMAPT | |
| SCHEMBL2119420 | 0.81 | CYP3A4 (0.44) | MAPTCYP2D6 | |
| SCHEMBL1049567 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2FFAR1MGLL | |
| SCHEMBL9849127 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2FFAR1MGLL | |
| SCHEMBL7528264 | 0.79 | TSHR (0.44) | GABRA1GABRB2MAPTL3MBTL1CYP2D6 | |
| SCHEMBL1584216 | 0.79 | LIPG (0.50) | — | |
| SCHEMBL7672866 | 0.79 | L3MBTL1 (0.34) | GABRA1GABRB2FFAR1MAPTNPSR1 | |
| SCHEMBL873220 | 0.78 | FFAR1 (0.44) | FFAR1MAPTL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 614 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | claimed |
| CN-114933620-A | Azithromycin derivatives having epithelial barrier enhancing properties | 艾比恩多制药有限责任公司 | 2022-08-23 | — | — | CN | claimed |
| CN-114681473-A | Application of glucosamine and derivatives thereof as anti-novel coronavirus drugs | 南湖实验室 | 2022-07-01 | — | — | CN | claimed |
| CN-108290919-B | Azithromycin derivatives having epithelial barrier enhancing properties | 艾比恩多制药有限责任公司 | 2022-06-17 | — | — | CN | claimed |
| US-20220106349-A1 | Compounds | EPIENDO PHARMACEUTICALS EHF (IS) | 2022-04-07 | — | — | US | claimed |
| US-11236120-B2 | Azithromycin derivatives with epithelial barrier enhancement properties | EPIENDO PHARMACEUTICALS EHF (IS) | 2022-02-01 | — | — | US | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| CN-112336733-A | Application of glucosamine and derivatives thereof as anti-novel coronavirus drugs | 南湖实验室 | 2021-02-09 | — | — | CN | claimed |
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | claimed |
| US-20200317710-A1 | Azithromycin Derivatives With Epithelial Barrier Enhancement Properties | EPIENDO PHARMACEUTICALS EHF (IS) | 2020-10-08 | — | — | US | claimed |
| US-5843946-A | α-and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1998-12-01 | — | — | US | claimed |
| EP-0815069-A1 | METHOD FOR SYNTHESISING 2-ETHYL-ANTHRAQUINONE | ELF ATOCHEM S.A. (FR) | 1998-01-07 | — | — | EP | claimed |
| EP-0810209-A2 | Alpha - and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1997-12-03 | — | — | EP | claimed |
| WO-1996028410-A1 | METHOD FOR SYNTHESISING 2-ETHYL-ANTHRAQUINONE | ELF ATOCHEM S.A. (FR) | 1996-09-19 | — | — | WO | claimed |
| EP-0715618-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | claimed |
| EP-0656887-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-06-14 | — | — | EP | claimed |
| WO-1995006030-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | claimed |
| WO-1994004492-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | claimed |
| US-4727079-A | Brain-specific dopaminergic activity involving dihydropyridine carboxamides, dihydroquinoline and isoquinoline carboxamides | UNIVERSITY OF FLORIDA (US) | 1988-02-23 | — | — | US | claimed |
| US-3988345-A | HYPOTENSIVE AGENTS; PHOSPHORUS OXYCHLORIDE | CHEMIE LINZ AKTIENGESELLSCHAFT (OE) | 1976-10-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | GABRA1 4588/4885GABRB2 3615/4885FFAR1 4328/4885 |
| US-20220106349-A1 | Compounds | CFTR, AQP1, CTSA | GABRA1 4809/4885GABRB2 4718/4885FFAR1 4475/4885 |
| US-11236120-B2 | Azithromycin derivatives with epithelial barrier enhancement properties | CFTR, AQP1, CTSA | GABRA1 4781/4885GABRB2 4699/4885FFAR1 4627/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | GABRA1 4588/4885GABRB2 3615/4885FFAR1 4328/4885 |
| US-20200317710-A1 | Azithromycin Derivatives With Epithelial Barrier Enhancement Properties | CFTR, AQP1, CTSA | GABRA1 4781/4885GABRB2 4699/4885FFAR1 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.