Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | CD69 | Q07108 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113590 | 0.79 | PTGDR2 (0.46) | HPGDPTGDR2KMT2ATHRATHRB | |
| SCHEMBL8413020 | 0.78 | KMT2A (0.42) | HPGDKMT2ATHRATHRBCD69 | |
| SCHEMBL10495757 | 0.73 | THRA (0.40) | KMT2ATHRATHRBCD69ELANE | |
| SCHEMBL14040248 | 0.72 | THRA (0.46) | KMT2ATHRATHRBCD69ELANE | |
| SCHEMBL10495694 | 0.72 | THRA (0.39) | KMT2ATHRATHRBCD69ELANE | |
| SCHEMBL14139324 | 0.71 | THRA (0.41) | KMT2ATHRATHRBCD69ELANE | |
| SCHEMBL17643210 | 0.71 | KMT2A (0.48) | KMT2ATHRATHRBCD69ELANE | |
| SCHEMBL10495772 | 0.70 | GPR17 (0.38) | HPGDKMT2ATHRATHRBALDH1A1 | |
| SCHEMBL8414572 | 0.70 | KDM4E (0.40) | HPGDKMT2ATHRATHRBCD69 | |
| SCHEMBL22359890 | 0.69 | THRA (0.50) | HPGDPTGDR2KMT2ATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4869913-A | DIETETICS | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| US-4522839-A | 3-Substituted 2,4,6-trihalogenated benzamides as sweetening agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | disclosed |
| US-4429152-A | DIABETES, DIETETICS | SCHERING, AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |