Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PCNA | P12004 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696076 | 0.75 | LMNA (0.53) | GPR17FFAR1HPGDFFAR4NPSR1 | |
| SCHEMBL10495782 | 0.72 | GPR17 (0.38) | GPR17FFAR1HPGDFFAR4NPSR1 | |
| SCHEMBL9637092 | 0.71 | GPR17 (0.57) | GPR17FFAR1FFAR4NPSR1PCNA | |
| SCHEMBL10495696 | 0.70 | HPGD (0.42) | ALDH1A1HPGDKMT2ATHRATHRB | |
| SCHEMBL10495683 | 0.69 | GPR17 (0.38) | GPR17FFAR1KDM4EALDH1A1GLA | |
| SCHEMBL20756505 | 0.69 | TSHR (0.42) | GPR17KDM4EALDH1A1GLAGAA | |
| SCHEMBL7416187 | 0.68 | FFAR1 (0.38) | FFAR1KDM4EALDH1A1GLAGAA | |
| SCHEMBL10495681 | 0.68 | GPR17 (0.38) | GPR17FFAR1KDM4EALDH1A1GLA | |
| SCHEMBL8095483 | 0.66 | CYP1A2 (0.50) | GPR17ALDH1A1NPSR1MAPK1HIF1A | |
| SCHEMBL10495691 | 0.65 | TTR (0.52) | KDM4EALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4869913-A | DIETETICS | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| US-4522839-A | 3-Substituted 2,4,6-trihalogenated benzamides as sweetening agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | disclosed |
| US-4429152-A | DIABETES, DIETETICS | SCHERING, AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |