Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509638 | 0.88 | ATM (0.77) | ATML3MBTL1KMT2ANAMPTPIK3CD | |
| SCHEMBL17203603 | 0.88 | ATM (0.77) | ATML3MBTL1KMT2ANAMPTPIK3CD | |
| SCHEMBL6034582 | 0.87 | ATM (0.97) | ATML3MBTL1KMT2ANAMPTPIK3CD | |
| SCHEMBL5250912 | 0.87 | ATM (0.75) | ATML3MBTL1KMT2ANAMPTDRD2 | |
| SCHEMBL2848208 | 0.85 | ATM (0.63) | ATML3MBTL1KMT2ANAMPTPIK3CD | |
| SCHEMBL10496006 | 0.82 | L3MBTL1 (0.72) | ATML3MBTL1KMT2ANAMPTLMNA | |
| SCHEMBL28239056 | 0.81 | KMT2A (0.55) | ATML3MBTL1KMT2ANAMPTCA2 | |
| SCHEMBL4059362 | 0.81 | ATM (0.66) | ATML3MBTL1KMT2ANAMPTPIK3CD | |
| SCHEMBL17213926 | 0.80 | ATM (0.71) | ATML3MBTL1KMT2ANAMPTPIK3CD | |
| SCHEMBL12335292 | 0.78 | ATM (0.59) | ATML3MBTL1KMT2ANAMPTPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734510-A | HYPOTENSIVE AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1988-03-29 | — | — | US | claimed |
| US-4808715-A | HYPERTENSIVE AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1989-02-28 | — | — | US | disclosed |
| US-4734510-A | HYPOTENSIVE AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1988-03-29 | — | — | US | disclosed |
| US-4640920-A | HYPOTENSIVE AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1987-02-03 | — | — | US | disclosed |