Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236893 | 0.62 | — | — | |
| SCHEMBL5202819 | 0.61 | LIG1 (0.30) | — | |
| SCHEMBL10071225 | 0.59 | KDM1A (0.50) | MEN1CYP2C19KMT2A | |
| SCHEMBL9452606 | 0.59 | — | — | |
| SCHEMBL10496172 | 0.58 | LMNA (0.40) | MEN1KMT2A | |
| SCHEMBL4690942 | 0.58 | ACHE (0.30) | — | |
| SCHEMBL10071236 | 0.57 | MEN1 (0.47) | MEN1CYP2C19KMT2A | |
| SCHEMBL10496241 | 0.57 | GLI1 (0.33) | — | |
| SCHEMBL11225147 | 0.57 | LMNA (0.32) | — | |
| SCHEMBL18951156 | 0.57 | TDP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861925-A | Process for the preparation of nitroolefins | W. R. GRACE & CO.-CONN. (US) | 1989-08-29 | — | — | US | disclosed |