Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442070 | 0.82 | CYP1A2 (0.50) | TAAR1CYP1A2ADRA1ACYP3A4 | |
| SCHEMBL20562309 | 0.81 | TAAR1 (0.52) | TAAR1CYP1A2ADRA1AHTR2AHTR2C | |
| SCHEMBL8009626 | 0.80 | CYP1A2 (0.44) | TAAR1CYP1A2MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1093815 | 0.80 | CYP1A2 (0.48) | TAAR1CYP1A2ADRA1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL27229034 | 0.79 | TAAR1 (0.50) | TAAR1CYP1A2ADRA1AHTR2AHTR2C | |
| SCHEMBL9198298 | 0.78 | USP2 (0.44) | TAAR1CYP1A2MAPK1CYP3A4 | |
| SCHEMBL20562959 | 0.78 | TAAR1 (1.00) | TAAR1CYP1A2ADRA1AHTR2AHTR2C | |
| SCHEMBL13564259 | 0.78 | CYP1A2 (0.43) | TAAR1CYP1A2MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL27229033 | 0.78 | PTGS2 (0.53) | TAAR1CYP1A2HTR2AHTR2CHTR2B | |
| SCHEMBL2096172 | 0.77 | ALDH1A1 (0.50) | CYP1A2MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118280-A1 | 4-ALKENYL AND 4-ALKYNYL PHENETHYLAMINE DERIVATIVES AND RELATED COMPOUNDS WITH MODIFIED DOM-LIKE ACTION | Mind Medicine, Inc. (US) | 2024-06-06 | — | — | WO | disclosed |
| US-20240174594-A1 | 4-ALKENYL AND 4-ALKYNYL PHENETHYLAMINE DERIVATIVES AND RELATED COMPOUNDS WITH MODIFIED DOM-LIKE ACTION | Mind Medicine, Inc. (US) | 2024-05-30 | — | — | US | disclosed |
| EP-2897599-B1 | SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES | UNIV TEMPLE (US) | 2020-12-30 | — | — | EP | disclosed |
| CN-110776447-A | Substituted alkyl diaryl derivatives, preparation method and use | 坦普尔大学 | 2020-02-11 | — | — | CN | disclosed |
| US-10207989-B2 | Substituted alkyl diaryl derivatives, methods of preparation and uses | Temple University—Of the Commonwealth System of Higher Education (US) | 2019-02-19 | — | — | US | disclosed |
| EP-2318126-B1 | WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE | UNIV TEXAS (US) | 2018-08-22 | — | — | EP | disclosed |
| US-20150266819-A1 | SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2015-09-24 | — | — | US | disclosed |
| EP-2897599-A2 | SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES | Temple University - Of The Commonwealth System of Higher Education (US) | 2015-07-29 | — | — | EP | disclosed |
| WO-2014047110-A2 | SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2014-03-27 | — | — | WO | disclosed |
| EP-2551675-A1 | Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods fo their preparation and their use | Chiron AS (NO) | 2013-01-30 | — | — | EP | disclosed |
| US-5486597-A | GASTRIN ANTAGONIST AS ANTISECRETORY AGENTS OF GASTRIC JUICE FOR STOMACH CANCER | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |
| US-5480871-A | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | CHIRON CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| WO-1995027729-A1 | OPIATE RECEPTOR LIGANDS | CHIRON CORPORATION (US) | 1995-10-19 | — | — | WO | disclosed |
| EP-0671928-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5447916-A | Hypotensive agents | CHIRON CORPORATION (US) | 1995-09-05 | — | — | US | disclosed |
| WO-1995004072-A1 | PEPTOID ALPHA-1 ADRENERGIC RECEPTOR LIGANDS | CHIRON CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |
| WO-1994006451-A1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORPORATION (US) | 1994-03-31 | — | — | WO | disclosed |
| EP-0563132-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES. | BLACK JAMES FOUNDATION (GB) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011284-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | THE JAMES BLACK FOUNDATION LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |
| US-4681888-A | Thienopyridine derivatives and anti-thrombotic compositions containing the same | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1987-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266819-A1 | SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES | CCNY, CCNB3, BOD1L1 | TAAR1 1550/4885CYP1A2 182/4885ADRA1A 995/4885 |
| US-10207989-B2 | Substituted alkyl diaryl derivatives, methods of preparation and uses | CCNY, CCNB3, BOD1L1 | TAAR1 1550/4885CYP1A2 182/4885ADRA1A 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.