Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497584 | 1.00 | ABCG2 (0.52) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL10497656 | 0.91 | ABCG2 (0.45) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL10871407 | 0.91 | THRB (0.54) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL10871409 | 0.91 | THRB (0.54) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL10871106 | 0.91 | THRB (0.54) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL10871104 | 0.91 | THRB (0.54) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL10497832 | 0.90 | ABCG2 (0.65) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL10498124 | 0.90 | ABCG2 (0.65) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL10497801 | 0.90 | ABCG2 (0.65) | ABCG2THRATHRBMAPTLMNA | |
| SCHEMBL9342195 | 0.89 | MAOB (0.56) | ABCG2THRATHRBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |