SCHEMBL10498124

SCHEMBL10498124

CCCCCCCCCCSc1ccc(C=CC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 3/20 0.65
▸ MAPT P10636 5/20 0.61
▸ RAB9A P51151 4/20 0.61
▸ KMT2A Q03164 4/20 0.61
▸ MEN1 O00255 3/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ LMNA P02545 1/20 0.61
▸ GAA P10253 1/20 0.61
▸ CASP3 P42574 1/20 0.61
▸ SENP8 Q96LD8 1/20 0.61
▸ SENP7 Q9BQF6 1/20 0.61
▸ SENP6 Q9GZR1 1/20 0.61
▸ F3 P13726 3/20 0.57
▸ MAOB P27338 4/20 0.55
▸ MAOA P21397 2/20 0.55
▸ POLB P06746 1/20 0.55
▸ ESR1 P03372 1/20 0.51
▸ ESR2 Q92731 1/20 0.51
▸ CXCL12 P48061 1/20 0.51
▸ P4HB P07237 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10497801 1.00 ABCG2 (0.65) ABCG2MAPTRAB9AKMT2AMEN1
SCHEMBL10497832 1.00 ABCG2 (0.65) ABCG2MAPTRAB9AKMT2AMEN1
SCHEMBL10497584 0.90 ABCG2 (0.52) ABCG2MAPTRAB9AKMT2AMEN1
SCHEMBL10497568 0.90 ABCG2 (0.52) ABCG2MAPTRAB9AKMT2AMEN1
SCHEMBL10498827 0.89 ABCG2 (0.51) ABCG2MAPTRAB9AKMT2AMEN1
SCHEMBL9342195 0.89 MAOB (0.56) ABCG2MAPTKMT2AMEN1LMNA
SCHEMBL10498351 0.89 TNFRSF1A (0.58) ABCG2MAPTRAB9AKMT2AMEN1
SCHEMBL9337932 0.89 MAOB (0.56) ABCG2MAPTKMT2AMEN1LMNA
SCHEMBL10497613 0.89 MAOB (0.55) ABCG2MAPTRAB9AKMT2AMEN1
SCHEMBL10497796 0.89 ABCG2 (0.51) ABCG2MAPTRAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
EP-0328669-A1 CHALCONE DERIVATIVE COMPOUNDS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MAPT 3297/4885RAB9A 480/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAPT 3512/4885RAB9A 1327/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAPT 3512/4885RAB9A 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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