Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 11/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.45 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497705 | 0.89 | THRA (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497709 | 0.86 | THRA (0.52) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497532 | 0.86 | THRA (0.52) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498768 | 0.86 | THRA (0.47) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497344 | 0.85 | THRA (0.51) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497522 | 0.85 | THRA (0.46) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL9341440 | 0.84 | SMN1; SMN2 (0.46) | TDP1 | |
| SCHEMBL10497704 | 0.83 | ATG4B (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL9338240 | 0.83 | THRA (0.49) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498041 | 0.82 | THRA (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |