Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.67 |
| ▸ | ATP4B | P51164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650844 | 0.88 | ATP4A (0.62) | ATP4AATP4B | |
| SCHEMBL9653892 | 0.88 | ATP4A (0.59) | ATP4AATP4B | |
| SCHEMBL9652118 | 0.88 | ATP4A (0.86) | ATP4AATP4B | |
| SCHEMBL30436929 | 0.86 | POLB (0.59) | — | |
| SCHEMBL31307844 | 0.85 | MAPT (0.69) | — | |
| SCHEMBL11244223 | 0.85 | MAPT (0.69) | — | |
| SCHEMBL9723912 | 0.85 | ATP4A (0.74) | ATP4AATP4B | |
| SCHEMBL9650838 | 0.85 | ATP4A (0.85) | ATP4AATP4B | |
| SCHEMBL10499317 | 0.85 | ATP4A (0.68) | ATP4AATP4B | |
| Hydrochloric Acid SCHEMBL11241211 | 0.84 | MAPT (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806549-A | INHIBITOR OF GASTRIC ACID SECRETION | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |
| US-4806550-A | 4-Amino-3-carbonyl substituted quinolines as inhibitors of gastric acid secretion | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |
| WO-1988001621-A1 | 4-AMINOQUINOLINE DERIVATIVES AND THEIR USE AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-03-10 | — | — | WO | disclosed |
| EP-0259174-A1 | Derivatives of 4-aminoquinoline and their use as medicaments | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-03-09 | — | — | EP | disclosed |