Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.59 |
| ▸ | ATP4B | P51164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650844 | 0.90 | ATP4A (0.62) | ATP4AATP4B | |
| SCHEMBL7187992 | 0.90 | ATP4A (0.64) | ATP4AATP4B | |
| SCHEMBL10498699 | 0.88 | ATP4A (0.67) | ATP4AATP4B | |
| SCHEMBL5930153 | 0.86 | CSF1R (0.66) | — | |
| SCHEMBL9653394 | 0.86 | MAPT (0.52) | — | |
| SCHEMBL9652793 | 0.85 | ATP4A (0.53) | ATP4AATP4B | |
| SCHEMBL9653897 | 0.84 | ATP4A (0.58) | ATP4AATP4B | |
| SCHEMBL5929736 | 0.83 | PDE4B (0.59) | — | |
| SCHEMBL9510303 | 0.83 | — | — | |
| SCHEMBL23493778 | 0.82 | MAPT (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259174-B1 | DERIVATIVES OF 4-AMINOQUINOLINE AND THEIR USE AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-03-18 | — | — | EP | claimed |