⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498813 | 0.93 | — | — | |
| SCHEMBL10499040 | 0.89 | ATP4A (0.68) | — | |
| SCHEMBL9650832 | 0.84 | ATP4A (0.80) | — | |
| SCHEMBL9653864 | 0.82 | — | — | |
| SCHEMBL9653475 | 0.81 | ATP4A (0.69) | — | |
| SCHEMBL9650906 | 0.81 | ATP4A (0.69) | — | |
| SCHEMBL10499074 | 0.80 | ATP4A (0.68) | — | |
| SCHEMBL9650890 | 0.79 | ATP4A (0.69) | — | |
| Hydrochloric Acid SCHEMBL9652082 | 0.79 | ATP4A (0.68) | — | |
| SCHEMBL9650838 | 0.78 | ATP4A (0.85) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806549-A | INHIBITOR OF GASTRIC ACID SECRETION | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |
| US-4806550-A | 4-Amino-3-carbonyl substituted quinolines as inhibitors of gastric acid secretion | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |
| WO-1988001621-A1 | 4-AMINOQUINOLINE DERIVATIVES AND THEIR USE AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-03-10 | — | — | WO | disclosed |
| EP-0259174-A1 | Derivatives of 4-aminoquinoline and their use as medicaments | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-03-09 | — | — | EP | disclosed |