Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.69 |
| ▸ | ATP4B | P51164 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9652082 | 0.99 | ATP4A (0.68) | ATP4AATP4B | |
| SCHEMBL9650757 | 0.92 | ATP4A (0.72) | ATP4AATP4B | |
| SCHEMBL9650906 | 0.92 | ATP4A (0.69) | ATP4AATP4B | |
| SCHEMBL10620602 | 0.92 | ATP4A (0.77) | ATP4AATP4B | |
| SCHEMBL9652198 | 0.89 | ATP4A (0.79) | ATP4AATP4B | |
| SCHEMBL9650838 | 0.88 | ATP4A (0.85) | ATP4AATP4B | |
| SCHEMBL9652885 | 0.85 | ATP4A (0.74) | ATP4AATP4B | |
| SCHEMBL451221 | 0.82 | ATP4A (1.00) | ATP4AATP4B | |
| SCHEMBL29402089 | 0.82 | ATP4A (1.00) | ATP4AATP4B | |
| SCHEMBL9653394 | 0.82 | MAPT (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259174-B1 | DERIVATIVES OF 4-AMINOQUINOLINE AND THEIR USE AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-03-18 | — | — | EP | claimed |
| US-4806549-A | INHIBITOR OF GASTRIC ACID SECRETION | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-21 | — | — | US | claimed |
| EP-0259174-A1 | Derivatives of 4-aminoquinoline and their use as medicaments | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-03-09 | — | — | EP | claimed |
| EP-0259174-B1 | DERIVATIVES OF 4-AMINOQUINOLINE AND THEIR USE AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-03-18 | — | — | EP | disclosed |
| US-4806549-A | INHIBITOR OF GASTRIC ACID SECRETION | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |
| US-4806550-A | 4-Amino-3-carbonyl substituted quinolines as inhibitors of gastric acid secretion | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |
| EP-0259174-A1 | Derivatives of 4-aminoquinoline and their use as medicaments | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-03-09 | — | — | EP | disclosed |