SCHEMBL10499153

SCHEMBL10499153

CC(CCC(N)=O)(CC(N)=O)C(N)=O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3504209 0.82 LMNA (0.41) CYP2D6TSHRCYP2C19HIF1A
SCHEMBL28124529 0.78
SCHEMBL14094284 0.77
SCHEMBL22326592 0.76 CYP2D6 (0.33) CYP2D6TSHRCYP2C19HIF1A
SCHEMBL3293803 0.75 LMNA (0.38) CYP2C19
SCHEMBL19438340 0.74 SOAT1 (0.47) CYP2C19
Hydrochloric Acid SCHEMBL6214815 0.73 LMNA (0.36) CYP2C19
SCHEMBL960674 0.72 KDM4E (0.40) CYP2D6TSHRCYP2C19HIF1A
SCHEMBL179561 0.72
Hydrochloric Acid SCHEMBL3350621 0.70 KDM4E (0.38) CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed