SCHEMBL22326592

SCHEMBL22326592

CCC(C)(CC(N)=O)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276842 0.84
SCHEMBL3000508 0.83 TSHR (0.35) CYP2D6TSHRCYP2C19HIF1A
Propionamide SCHEMBL17925395 0.82 MAPT (0.33) CYP2C19LMNAHSD17B10KDM4E
SCHEMBL3504209 0.81 LMNA (0.41) CYP2D6TSHRCYP2C19HIF1ALMNA
SCHEMBL16938896 0.77
SCHEMBL5955337 0.77
SCHEMBL10499153 0.76 CYP2D6 (0.31) CYP2D6TSHRCYP2C19HIF1A
SCHEMBL7763609 0.75 LMNA (0.43) TSHRLMNAHSD17B10
SCHEMBL30375370 0.75 LMNA (0.34) TSHRLMNAHSD17B10KDM4E
SCHEMBL276192 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101747455-B Supported main catalyst for olefin polymerization and preparation method thereof PETROCHINA CO LTD 2012-03-07 CN claimed
CN-101747456-B Polypropylene catalyst and preparation method thereof PETROCHINA CO LTD 2012-03-07 CN claimed
CN-101747455-A Supported main catalyst for olefin polymerization and preparation method thereof PETROCHINA CO LTD 2010-06-23 CN claimed
CN-101747456-A Polypropylene catalyst and preparation method thereof PETROCHINA CO LTD 2010-06-23 CN claimed
US-10738139-B2 Decarboxylation and amidation of polyitaconic acid polymers ITACONIX CORPORATION (US) 2020-08-11 US disclosed
CN-101747455-B Supported main catalyst for olefin polymerization and preparation method thereof PETROCHINA CO LTD 2012-03-07 CN disclosed
CN-101747456-B Polypropylene catalyst and preparation method thereof PETROCHINA CO LTD 2012-03-07 CN disclosed
CN-101747455-A Supported main catalyst for olefin polymerization and preparation method thereof PETROCHINA CO LTD 2010-06-23 CN disclosed
CN-101747456-A Polypropylene catalyst and preparation method thereof PETROCHINA CO LTD 2010-06-23 CN disclosed