Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498967 | 0.88 | FAAH (0.44) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL8413025 | 0.86 | GAA (0.55) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11232767 | 0.85 | GAA (0.44) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11220004 | 0.84 | GAA (0.52) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11232629 | 0.83 | CYP1A2 (0.48) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11226349 | 0.83 | GAA (0.43) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11219762 | 0.82 | GAA (0.41) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11228333 | 0.82 | GAA (0.41) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11221721 | 0.80 | GAA (0.45) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11224831 | 0.80 | GAA (0.40) | GAAMGAMSIMGAM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822814-A | PREVENTING OR TREATING LIVER DISORDERS; FUNGICIDES; OR PREVENTING ACCUMULATION OF FAT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0242061-A2 | New 1,3-dithiol-2-ylidene-alkylsulfonylacetates and their uses | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1987-10-21 | — | — | EP | disclosed |