Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549626 | 1.00 | WDR5 (0.56) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL599946 | 0.89 | WDR5 (0.50) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL29486321 | 0.89 | WDR5 (0.50) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL27590889 | 0.89 | WDR5 (0.50) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| Hydrazine SCHEMBL8923125 | 0.87 | WDR5 (0.63) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6371536 | 0.87 | LDHA (0.52) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL29376013 | 0.86 | WDR5 (0.68) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL33850 | 0.86 | WDR5 (0.68) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL27804512 | 0.86 | WDR5 (0.68) | WDR5KDM4EKMT2AALDH1A1MEN1 | |
| Benzene SCHEMBL27549874 | 0.86 | WDR5 (0.68) | WDR5KDM4EKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014066613-A2 | SPHINGOLIPID METABOLITE MIMETICS | ZHEJIANG UNIVERSITY (CN) | 2014-05-01 | — | — | WO | claimed |
| CN-1353701-A | Peptidyl heterocyclic ketones useful as tryptase inhibitors | ORTHO MCNEIL PHARM INC (US) | 2002-06-12 | — | — | CN | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |