Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESRRG | P62508 | 2/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499104 | 0.81 | MLYCD (0.40) | MLYCDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10499479 | 0.79 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6882111 | 0.79 | ESR1 (0.50) | MAPTALDH1A1ESR1KDM4EESR2 | |
| SCHEMBL10499396 | 0.78 | MLYCD (0.41) | MLYCDMAPTALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL4630053 | 0.77 | MAPT (0.50) | MAPTALDH1A1ESR1KDM4EESR2 | |
| SCHEMBL151367 | 0.75 | KCNA3 (0.43) | MLYCDMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL6880118 | 0.74 | MAPT (0.56) | MAPTALDH1A1ESR1KDM4EAPP | |
| SCHEMBL10498896 | 0.74 | BCL9 (0.42) | MLYCDMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL9695555 | 0.73 | HRH3 (0.41) | MAPTALDH1A1KMT2AESR1KDM4E | |
| SCHEMBL9101850 | 0.71 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | claimed |
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |