Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581320 | 0.89 | POLB (0.54) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1954254 | 0.89 | POLB (0.54) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6570758 | 0.86 | POLB (0.51) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9115683 | 0.85 | GRIN2D (0.61) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29452944 | 0.85 | GRIN2D (0.61) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29581945 | 0.84 | POLB (0.53) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1955155 | 0.84 | POLB (0.53) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15094123 | 0.83 | POLB (0.64) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29580948 | 0.83 | POLB (0.64) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23808898 | 0.83 | NPC1 (0.64) | POLBHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171139-B1 | HIGH POLYMER STABILIZER CONTAINING A PHENOLIC COMPOUND, AND HIGH POLYMERS STABILIZED THEREBY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-07-26 | — | — | EP | disclosed |
| EP-0141502-B1 | PIPERIDINE DERIVATIVES, THEIR PRODUCTION, AND POLYMERS PHOTOSTABILIZED THEREBY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-01-25 | — | — | EP | disclosed |