Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019462 | 0.87 | POLB (0.58) | POLBSLC16A3LMNAHTTMAPT | |
| SCHEMBL10499689 | 0.86 | POLB (0.50) | POLBSLC16A3LMNAHTTMAPT | |
| SCHEMBL29580948 | 0.85 | POLB (0.64) | POLBSLC16A3HTTMAPTL3MBTL1 | |
| SCHEMBL15094123 | 0.85 | POLB (0.64) | POLBSLC16A3HTTMAPTL3MBTL1 | |
| SCHEMBL21551505 | 0.84 | MAPT (0.60) | POLBLMNAHTTMAPTNPSR1 | |
| SCHEMBL23808898 | 0.84 | NPC1 (0.64) | POLBSLC16A3LMNAMAPTHDAC3 | |
| SCHEMBL1644901 | 0.83 | MAPK1 (0.56) | POLBSLC16A3HTTHDAC3HDAC4 | |
| SCHEMBL29581320 | 0.83 | POLB (0.54) | POLBSLC16A3MAPTHDAC3HDAC4 | |
| SCHEMBL1954254 | 0.83 | POLB (0.54) | POLBSLC16A3MAPTHDAC3HDAC4 | |
| SCHEMBL16532204 | 0.83 | SLC16A3 (0.61) | POLBSLC16A3LMNAMAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406866-A1 | INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | Idun Pharmaceuticals, Inc. (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003008374-A1 | INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2003-01-30 | — | — | WO | disclosed |
| US-3987192-A | ANTIALLERGENS AND ANTIANAPHYLAXID; 2'-CYANO-OXANILIC ACID | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |