SCHEMBL9115683

SCHEMBL9115683

CCc1ccccc1NC(=O)C(N)=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.61
GRIN3B O60391 1/20 0.61
GRIN1 Q05586 1/20 0.61
GRIN2A Q12879 1/20 0.61
GRIN2B Q13224 1/20 0.61
GRIN2C Q14957 1/20 0.61
GRIN3A Q8TCU5 1/20 0.61
SIGMAR1 Q99720 1/20 0.61
MAPT P10636 6/20 0.57
ALDH1A1 P00352 4/20 0.57
GAA P10253 2/20 0.57
HTT P42858 2/20 0.55
LMNA P02545 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
POLB P06746 2/20 0.53
HDAC3 O15379 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29452944 1.00 GRIN2D (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2349955 0.88 MAPT (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Phenetole SCHEMBL27341933 0.87 GRIN2D (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29581227 0.86 MAPT (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1953684 0.86 MAPT (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10499689 0.85 POLB (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL28825350 0.85 MAPT (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9501342 0.84 MAPT (0.65) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL21551505 0.83 MAPT (0.60) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10585430 0.82 GAA (0.55) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221542-A Synthesis method of N- (2-ethoxyphenyl) -N' - (2-ethylphenyl) -oxamide 常州永和精细化学有限公司 2024-06-21 CN disclosed
CN-117836384-A Single layer adhesive film and related articles 3M创新有限公司 2024-04-05 CN disclosed
CN-115572238-B Preparation method of N- (2-ethoxyphenyl) -N' - (2-ethylphenyl) -oxamide 常州永和精细化学有限公司 2023-10-17 CN disclosed
CN-115572238-A Preparation method of N- (2-ethoxyphenyl) -N' - (2-ethylphenyl) -oxamide 常州永和精细化学有限公司 2023-01-06 CN disclosed
EP-3681291-A1 NEW AGROCHEMICAL FORMULATIONS BASF SE (DE) 2020-07-22 EP disclosed
WO-2019052898-A1 NEW AGROCHEMICAL FORMULATIONS BASF SE (DE) 2019-03-21 WO disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
EP-3443033-A1 POYCARBONATE COMPOSITIONS CONTAINING ISOSORBIDE DIESTERS Covestro Deutschland AG (DE) 2019-02-20 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
CN-108679333-A A kind of circumference braiding composite hose and preparation method thereof 南京砺行节水技术有限责任公司 2018-10-19 CN disclosed
EP-2519532-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-03-08 EP disclosed
US-20160168180-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP 2016-06-16 US disclosed
US-9283555-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2016-03-15 US disclosed
US-20140221645-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-08-07 US disclosed
US-8680003-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-03-25 US disclosed
US-20120309965-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-12-06 US disclosed
EP-2519532-A1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS Chevron Phillips Chemical Company LP (US) 2012-11-07 EP disclosed
CN-1285656-C Fluorescent pigment composition CLARIANT INT LTD (GB) 2006-11-22 CN disclosed
CN-1628147-A Fluorescent pigment composition CLARIANT INT LTD (GB) 2005-06-15 CN disclosed
WO-1995010790-A1 HIGH REFRACTIVE INDEX PHOTOCHROMIC OPHTHALMIC ARTICLE PPG INDUSTRIES, INC. (US) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 GRIN2D 1074/4885GRIN3B 480/4885GRIN1 317/4885
US-20120309965-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 GRIN2D 1074/4885GRIN3B 480/4885GRIN1 317/4885
US-20160168180-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 GRIN2D 1074/4885GRIN3B 480/4885GRIN1 317/4885
US-20140221645-A1 Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins NIT2, NCLN, NPM1 GRIN2D 1074/4885GRIN3B 480/4885GRIN1 317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.