Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 2/20 | 0.46 |
| ▸ | TGM2 | P21980 | 2/20 | 0.46 |
| ▸ | TGM1 | P22735 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499958 | 0.88 | MEN1 (0.57) | MEN1KMT2ANPSR1MAPTCYP2C19 | |
| SCHEMBL10500450 | 0.87 | MEN1 (0.49) | MEN1KMT2ANPSR1MAPTCYP2C19 | |
| SCHEMBL10500526 | 0.85 | PYGL (0.53) | MEN1KMT2ANPSR1MAPTCYP2C19 | |
| SCHEMBL10500298 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2ANPSR1MAPTCYP2C19 | |
| SCHEMBL10500187 | 0.84 | MEN1 (0.50) | MEN1KMT2ANPSR1MAPTCYP2C19 | |
| SCHEMBL10501134 | 0.83 | PYGL (0.47) | MEN1KMT2ANPSR1CYP2C19SMN1; SMN2 | |
| SCHEMBL10500385 | 0.82 | MEN1 (0.45) | MEN1KMT2ANPSR1MAPTCYP2C19 | |
| SCHEMBL11113119 | 0.82 | KDM4E (0.43) | MEN1KMT2ANPSR1MAPTTSHR | |
| SCHEMBL10500129 | 0.82 | SCN5A (0.49) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL10500603 | 0.82 | KMT2A (0.44) | MEN1KMT2ANPSR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-B1 | N-ARYL-ALPHA-AMINO-CARBOXAMIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-05-24 | — | — | EP | disclosed |