Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137799 | 0.80 | MAPT (0.49) | MAPTHTTSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL17137784 | 0.80 | MAPT (0.49) | MAPTHTTSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL10401926 | 0.80 | MAPT (0.49) | MAPTHTTSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL5863090 | 0.80 | MAPT (0.49) | MAPTHTTSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL11227788 | 0.79 | ALDH1A1 (0.43) | MAPTHTTSMN1; SMN2DNM1TSHR | |
| SCHEMBL28047682 | 0.78 | MAPT (0.51) | MAPTHTTSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL28047683 | 0.78 | MAPT (0.51) | MAPTHTTSMN1; SMN2DNM1TSHR | |
| SCHEMBL168120 | 0.76 | MAPT (0.57) | MAPTHTTSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL7277860 | 0.76 | MAPT (0.68) | MAPTHTTSMN1; SMN2DNM1ALDH1A1 | |
| SCHEMBL29655470 | 0.76 | MAPT (0.41) | MAPTHTTSMN1; SMN2DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |