SCHEMBL28047683

SCHEMBL28047683

CC(C#N)C(O)CNc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.51
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
DNM1 Q05193 1/20 0.40
TSHR P16473 1/20 0.37
BCHE P06276 1/20 0.37
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 1/20 0.35
TRPA1 O75762 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21843138 0.80 MAPT (0.55) MAPTHTTSMN1; SMN2ADRB2ADRB1
SCHEMBL10500366 0.78 MAPT (0.49) MAPTHTTSMN1; SMN2ADRB2ADRB1
SCHEMBL1337104 0.78 MAPT (0.44) MAPTHTTSMN1; SMN2ADRB2ADRB1
SCHEMBL1674517 0.75 MAPT (0.58) MAPTHTTSMN1; SMN2ADRB2ADRB1
SCHEMBL16197831 0.75 MAPT (0.58) MAPTHTTSMN1; SMN2ADRB2ADRB1
SCHEMBL11227788 0.74 ALDH1A1 (0.43) MAPTHTTSMN1; SMN2DNM1TSHR
SCHEMBL5053147 0.71 TRPA1 (0.55) MAPTHTTSMN1; SMN2ADRB2ADRB1
Acetonitrile SCHEMBL27754235 0.71 MAPT (0.46) MAPTHTTSMN1; SMN2DNM1ALDH1A1
SCHEMBL7441732 0.71 MAPT (0.46) MAPTHTTSMN1; SMN2ADRB2ADRB1
SCHEMBL182877 0.71 MAPT (0.52) MAPTHTTSMN1; SMN2ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105111101-A Method for preparing N-cyanoethyl-N-ethoxylaniline by using ionic liquid HIGH & NEW TECHNOLOGY RES CT HENAN ACADEMY SCIENCE 2015-12-02 CN disclosed