Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10500661 | 1.00 | ALDH1A1 (0.30) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8825724 | 1.00 | ALDH1A1 (0.30) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8825721 | 1.00 | ALDH1A1 (0.30) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8826057 | 0.87 | MEN1 (0.33) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8826055 | 0.87 | MEN1 (0.33) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8825842 | 0.85 | PLIN1 (0.32) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8825947 | 0.85 | PLIN1 (0.32) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL9118305 | 0.85 | PLIN1 (0.32) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8826045 | 0.84 | CYP1A1 (0.36) | ALDH1A1 | |
| SCHEMBL10500521 | 0.84 | CYP1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816581-A | 4-(phenylthio or phenylsulfonyl) azetidinones and process of manufacture | HOFFMAN-LA ROCHE INC. (US) | 1989-03-28 | — | — | US | disclosed |
| EP-0179318-B1 | STERICAL UNIFORM 2-AZETIDINONES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1989-01-18 | — | — | EP | disclosed |
| EP-0179318-A1 | Sterical uniform 2-azetidinones | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-04-30 | — | — | EP | disclosed |