Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP51A1 | Q16850 | 5/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502053 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1LMNAGAATSHR | |
| SCHEMBL10501015 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1LMNAGAATSHR | |
| SCHEMBL10501501 | 0.76 | PDE3B (0.41) | SMN1; SMN2LMNAGAATSHRCYP17A1 | |
| SCHEMBL10502057 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1LMNAGAATSHR | |
| SCHEMBL10500916 | 0.72 | PDE3B (0.51) | SMN1; SMN2L3MBTL1LMNAGAACYP17A1 | |
| SCHEMBL10501018 | 0.72 | LMNA (0.49) | SMN1; SMN2L3MBTL1LMNAGAATSHR | |
| SCHEMBL10501673 | 0.70 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1LMNAGAATSHR | |
| SCHEMBL1242879 | 0.68 | SMN1; SMN2 (0.87) | SMN1; SMN2L3MBTL1LMNAGAATSHR | |
| SCHEMBL9830214 | 0.65 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1LMNAGAATSHR | |
| SCHEMBL906187 | 0.65 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170214-B1 | THE PREPARATION OF 1,3-DIHYDRO-4-PYRIDOYL-2H-IMIDAZOL-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-13 | — | — | EP | disclosed |