Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC11A2 | P49281 | 4/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | MAT2A | P31153 | 4/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749727 | 0.88 | MAT2A (0.47) | MAT2AKIF11TRPV1 | |
| SCHEMBL10502254 | 0.85 | SLC11A2 (0.39) | SLC11A2PDCD1CD274MAT2AKIF11 | |
| SCHEMBL5916905 | 0.83 | METAP2 (0.48) | SLC11A2 | |
| SCHEMBL5916813 | 0.80 | METAP2 (0.41) | — | |
| SCHEMBL5916573 | 0.80 | MAT2A (0.45) | PDCD1CD274MAT2A | |
| SCHEMBL5916754 | 0.80 | MPI (0.50) | SLC11A2 | |
| SCHEMBL10502403 | 0.80 | METAP2 (0.59) | MAT2A | |
| SCHEMBL30530469 | 0.79 | METAP2 (0.57) | — | |
| SCHEMBL1353489 | 0.79 | METAP2 (0.57) | — | |
| SCHEMBL5916746 | 0.78 | METAP2 (0.53) | SLC11A2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |