Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544347 | 0.90 | LOX (0.46) | LOXLOXL2ACACBFFAR1GSK3B | |
| SCHEMBL18082590 | 0.82 | LOX (0.51) | LOXLOXL2ACACBFFAR1GSK3B | |
| SCHEMBL16119318 | 0.81 | LOX (0.54) | LOXLOXL2ACACBFFAR1CNR1 | |
| SCHEMBL16228572 | 0.81 | LOX (0.54) | LOXLOXL2ACACBFFAR1CNR1 | |
| SCHEMBL30921159 | 0.80 | ALDH1A1 (0.41) | ACACB | |
| SCHEMBL23792323 | 0.78 | LOXL2 (0.55) | LOXLOXL2ACACBFFAR1GSK3B | |
| SCHEMBL9108487 | 0.74 | MIF (0.33) | ACACB | |
| SCHEMBL25355781 | 0.74 | LOX (0.49) | LOXLOXL2ACACBFFAR1CNR1 | |
| SCHEMBL25355776 | 0.74 | LOX (0.49) | LOXLOXL2ACACBFFAR1CNR1 | |
| SCHEMBL25357821 | 0.73 | LOX (0.55) | LOXLOXL2ACACBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163506-B1 | PROCESS FOR THE PREPARATION OF A PYRIDIL-PROPANOIC ACID | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-11-02 | — | — | EP | disclosed |
| EP-0163506-A2 | Process for the preparation of a pyridil-propanoic acid | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |